Alternative Causes of Cancer: The Relationship Between Cancer and Apoptosis
Dr Chanda Siddoo-Atwal, President of Moondust Cosmetics, is a cancer biologist with a specific interest in the mechanisms that lead to cancer. The classical theory of carcinogenesis involving failure of DNA repair mechanisms and the clonal expansion of mutated cells does not fit all carcinogens (cancer-causing agents). More recently, it has become apparent that the aberrant regulation of apoptosis (programmed cell death) may provide another mechanism to explain these exceptions. Dr Siddoo-Atwal’s research has centred around skin cancer and the need for effective novel sunscreens to protect against the development of UV-radiation induced skin cancer, which conforms to this new model.
Cancer is the second leading cause of death globally, accounting for around one in every six deaths in 2018. In particular, skin cancer is diagnosed in one in every three cases of cancer and this is set to increase due to climate change impacting the protective ozone layer around the Earth and allowing more UV radiation from the sun to reach the Earth’s surface.
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